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. 2022 Dec 2;163(5):1279–1291. doi: 10.1016/j.chest.2022.11.034

Table 2.

Impact of Different Strategies for Imputing Adherence Missing Values on Mean Adherence Value and Rate of Patients With Mean PAP Use of ≥ 4 h/night

Variable Study Period
1 mo 2 mo 3 mo
Missing values, mean (SD), No. 0.5 (2.6) 1.6 (5.9) 3.5 (11.2)
Maximum missing values, No. 29 58 86
All samples
 No strategy for missing values
 Individual average PAP adherence, mean (SD), h/night 4.61 (2.4) 4.62 (2.4) 4.6 (2.4)
 PAP-adherent patients,a No. (%) 257 (63) 255 (63) 255 (63)
 Replacing missing values by zeros
 Individual average PAP adherence, mean (SD), h/night 4.56 (2.4) 4.55 (2.4) 4.5 (2.4)
 PAP-adherent patients,a No. (%) 252 (62) 249 (61) 251 (62)
 Removing patients with missing values
 Individual average PAP adherence, mean (SD), h/night 4.69 (2.4) 4.85 (2.3) 4.89 (2.3)
 PAP-adherent patients,a No. (%) 239 (64) 230 (66) 221 (67)
 Patients with missing values, No. (%) 33 (8) 60 (15) 78 (19)
 No strategy for missing values
 Individual average PAP adherence, mean (SD), h/night 3.67 (2.4) 3.29 (2.4) 3.36 (2.4)
 PAP-adherent patients,a No. (%) 18 (55) 25 (42) 34 (44)
 Replacing missing values by zeros
 Individual average PAP adherence, mean (SD), h/night 3.0 (2.1) 2.78 (2.2) 2.86 (2.3)
 PAP-adherent patients,a No. (%) 13 (39) 19 (32) 30 (38)

Results are presented for two different populations: the entire sample (N = 407) and the subsample of patients for whom values are missing.

a

With mean PAP use ≥ 4 h/night.