Table 2: Characteristics of patients with diabetic foot ulcers (categorical values).
Risk factors | Total n (%) | Amputation n (%) | Non-amputation n (%) | p-value |
---|---|---|---|---|
Gangrenous Wagner* | 184/462 (39.8) | 161/274 (58.8) | 23/188 (12.2) | <0.001 |
Infection† | 393/456 (86.2) | 256/272 (94.1) | 137/184 (74.5) | <0.001 |
Severe bacterial infection‡ | 113/455 (24.8) | 93/271 (34.3) | 20/184 (10.9) | <0.001 |
Pathogenesis of ulcer | 363 | 244 | 119 | <0.001 |
Neuropathic | 164 (45.2) | 76 (31.1) | 88 (73.9) | |
Neuroischaemic | 132 (36.4) | 115 (47.1) | 17 (14.4) | |
I schaemic | 67 (18.5) | 53 (21.7) | 14 (11.8) | |
Neuropathy | 373/460 (81.1) | 220/284 (77.5) | 153/176 (86.9) | 0.012 |
Retinopathy | 229/300 (76.3) | 155/196 (79.1) | 74/104 (71.2) | 0.124 |
Nephropathy | 283/371 (76.3) | 178/224 (79.5) | 105/147 (71.4) | 0.075 |
Glomerular filtration rate <60 mL/min/1.73 m2 | 157/483 (32.5) | 102/282 (36.2) | 55/201 (35.0) | 0.042 |
Coronary vascular disease | 224/333 (67.3) | 164/235 (69.8) | 60/98 (61.2) | 0.129 |
Atherosclerotic peripheral arteries | 292/373 (78.3) | 235/256 (91.8) | 57/117 (48.7) | <0.001 |
Cerebral arterial disease | 81/226 (35.8) | 63/152 (41.4) | 18/74 (24.3) | 0.012 |
Hypertension | 403/480 (84.0) | 255/289 (88.2) | 148/191 (77.5) | 0.002 |
Chronic respiratory disease | 35/489 (7.2) | 23/295 (7.8) | 12/194 (6.2) | 0.499 |
Congestive heart failure | 67/488 (13.7) | 49/295 (16.6) | 18/193 (9.3) | 0.022 |
Hepatosteatosis | 111/217 (51.2) | 82/160 (51.3) | 29/57 (50.9) | 0.961 |
Being on dialysis with end-stage renal disease | 45/494 (9.1) | 38/298 (12.8) | 7/196 (3.6) | 0.001 |
Hypercholesterolaemia | 349/453 (77.0) | 241/274 (88.0) | 108/179 (60.3) | <0.001 |
Hypertriglyceridaemia | 170/453 (37.5) | 119/273 (43.6) | 51/180 (28.3) | 0.001 |
Hyperlipidaemia | 361/453 (79.7) | 243/274 (88.7) | 118/179 (65.9) | <0.001 |
*Gangrenous Wagner defined as Wagner scores 4 and 5.
†Defined as C-reactive protein >0.5 mg/dL.
‡Defined as C-reactive protein >10 mg/dL.