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. 2023 May 23;19(1):85–93. doi: 10.17925/EE.2023.19.1.85

Table 2: Characteristics of patients with diabetic foot ulcers (categorical values).

Risk factors Total n (%) Amputation n (%) Non-amputation n (%) p-value
Gangrenous Wagner* 184/462 (39.8) 161/274 (58.8) 23/188 (12.2) <0.001
Infection 393/456 (86.2) 256/272 (94.1) 137/184 (74.5) <0.001
Severe bacterial infection 113/455 (24.8) 93/271 (34.3) 20/184 (10.9) <0.001
Pathogenesis of ulcer 363 244 119 <0.001
Neuropathic 164 (45.2) 76 (31.1) 88 (73.9)
Neuroischaemic 132 (36.4) 115 (47.1) 17 (14.4)
I schaemic 67 (18.5) 53 (21.7) 14 (11.8)
Neuropathy 373/460 (81.1) 220/284 (77.5) 153/176 (86.9) 0.012
Retinopathy 229/300 (76.3) 155/196 (79.1) 74/104 (71.2) 0.124
Nephropathy 283/371 (76.3) 178/224 (79.5) 105/147 (71.4) 0.075
Glomerular filtration rate <60 mL/min/1.73 m2 157/483 (32.5) 102/282 (36.2) 55/201 (35.0) 0.042
Coronary vascular disease 224/333 (67.3) 164/235 (69.8) 60/98 (61.2) 0.129
Atherosclerotic peripheral arteries 292/373 (78.3) 235/256 (91.8) 57/117 (48.7) <0.001
Cerebral arterial disease 81/226 (35.8) 63/152 (41.4) 18/74 (24.3) 0.012
Hypertension 403/480 (84.0) 255/289 (88.2) 148/191 (77.5) 0.002
Chronic respiratory disease 35/489 (7.2) 23/295 (7.8) 12/194 (6.2) 0.499
Congestive heart failure 67/488 (13.7) 49/295 (16.6) 18/193 (9.3) 0.022
Hepatosteatosis 111/217 (51.2) 82/160 (51.3) 29/57 (50.9) 0.961
Being on dialysis with end-stage renal disease 45/494 (9.1) 38/298 (12.8) 7/196 (3.6) 0.001
Hypercholesterolaemia 349/453 (77.0) 241/274 (88.0) 108/179 (60.3) <0.001
Hypertriglyceridaemia 170/453 (37.5) 119/273 (43.6) 51/180 (28.3) 0.001
Hyperlipidaemia 361/453 (79.7) 243/274 (88.7) 118/179 (65.9) <0.001

*Gangrenous Wagner defined as Wagner scores 4 and 5.

Defined as C-reactive protein >0.5 mg/dL.

Defined as C-reactive protein >10 mg/dL.