Figure 1: Schematic of the progression of non-alcoholic fatty liver disease to cirrhosis and hepatocellular carcinoma.

About 25% of the population has NAFLD. Of those with NAFLD, 20% progress to NASH. About 5-20% of those with NASH progress to cirrhosis. Hepatocellular carcinoma may result in 5-13% of patients with cirrhosis secondary to NASH.

Used with permission from ©Mount Sinai HealthSystem.

NAFLD = non-alcoholic fatty liver disease; NASH = non-alcoholic steatohepatitis.