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. 2023 May 31;40(2):246–252. doi: 10.5114/ada.2023.127642

Table 2.

Allelic and genotypic frequencies of the rs66554220 variant (14 bp ID) and association study according to inheritance models

Inheritance models Healthy individuals n = 198 (%) Vitiligo patients n = 197 (%) (χ2) p-value OR [95% CI]
Allele:
 Del 109 (55) 111 (56) Reference
 Ins 89 (45) 86 (44) (0.05) 0.82 0.97 [0.73–1.28]
Co-dominant model:
 Del/Del 63 (31.82) 64 (32.49) Reference
 Del/Ins 92 (46.46) 92 (46.70) (0.00) 0.95 0.98 [0.63–1.55]
 Ins/Ins 43 (21.72) 41 (20.81) (0.05) 0.82 0.94 [0.54–1.63]
Dominant model:
 Del/Del 63 (31.82) 64 (32.49) Reference
 Del/Ins + Ins/Ins 135 (68.18) 133 (67.51) (0.02) 0.89 0.97 [0.64–1.48]
Recessive model:
 Del/Del + Del/Ins 155 (78.28) 156 (79.19) Reference
 Ins/Ins 43 (21.72) 41 (20.81) (0.05) 0.83 1.06 [0.65–1.71]

OR – odds ratio, χ2 – value of χ2, p-value – significance defined by χ2 test; 95% CI – confidence interval of 95%.