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. 2023 Jun 12;13:9516. doi: 10.1038/s41598-023-36144-x

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Adjusted linear effect on the cumulative number of ARI at the age of 4 years. Separate models show the association for each T cell repertoire index (Shannon diversity, Simpson diversity, richness, clonality) in comparison with the effect of older siblings, while mutually adjusting (n = 67). Estimates and 95% confidence intervals are shown. Estimates indicate number of additional infections. Analyses and data plotting were performed using RStudio (version 1.1.456).