Table 1.

Demographic characteristics of postmortem study specimens, by individual study groups and CTE staging

Study parameter	Entire	Controls,	AD only,	CTE only,	AD + CTE,
[Median (IQR)	cohort,	n = 9	n = 7	n = 15	n = 10
or n (%)]	n = 41
Age, y	72 (65–81)	63 (46–69)	81 (69.5–82.5)	69 (46.5–74.5)	81.5 (77.5–83.8)
Sex, Male	39 (95.1)	8 (88.9)	7 (100)	14 (93.3)	10 (100)
Braak Stage
0	10 (25.6)	5 (55.6)	0 (0)	5 (38.5)	0 (0)
I-II	4 (10.3)	3 (33.3)	0 (0)	1 (7.7)	0 (0)
III-IV	11 (28.2)	1 (11.1)	1 (14.3)	6 (46.2)	3 (30)
V-VI	14 (35.9)	0 (0)	6 (85.7)	1 (7.7)	7 (70)
CERAD Score
0	20 (48.8)	8 (88.9)	0 (0)	12 (80)	0 (0)
1	10 (24.4)	1 (11.1)	1 (14.3)	3 (20)	5 (50)
2	7 (17.1)	0 (0)	4 (57.1)	0 (0)	3 (30)
3	4 (9.8)	0 (0)	2 (28.6)	0 (0)	2 (20)
Study parameter	Entire	No CTE,		Low stage	High stage CTE
[Median (IQR)	cohort,	n = 16		CTE (Stage I	(Stage III or
or n (%)]	n = 41			or II), n = 5	IV), n = 20
Age, y	72 (65–81)	69 (58.8–75.8)		32 (27–46)	77.5 (69.8–83)
Sex, Male	39 (95.1)	15 (93.8)		5 (100)	19 (95)
Braak Stage
0	10 (25.6)	5 (31.2)		4 (80)	1 (5.6)
I-II	4 (10.3)	3 (18.8)		0 (0)	1 (5.6)
III-IV	11 (28.2)	2 (12.5)		0 (0)	9 (50)
V-VI	14 (35.9)	6 (37.5)		1 (20)	7 (38.9)
CERAD Score
0	20 (48.8)	8 (50)		4 (80)	8 (40)
1	10 (24.4)	2 (12.5)		0 (0)	8 (40)
2	7 (17.1)	4 (25)		1 (20)	2 (10)
3	4 (9.8)	2 (12.5)		0 (0)	2 (10)

IQR, Interquartile range; AD, Alzheimer’s disease; CTE, chronic traumatic encephalopathy.