. 2023 May 22;14(6):727–736. doi: 10.1021/acsmedchemlett.2c00495

Table 2. Selectivity of 36 and Human cAMP EP4 Receptor Antagonism IC₅₀^a.

compd	EP1	EP2	EP3	EP4
36	>10⁴	>10⁴	>10⁴	4.3
E7046	>10⁴	928.2	>10⁴	10.1 (13.5)^b
L-798106	^c	^c	33.02	^c

The data were taken as the average of two experimental values and are reported in nM.

Observed and reported values.¹⁸

Not determined.

Table 2. Selectivity of 36 and Human cAMP EP4 Receptor Antagonism IC50a.