Table 3. EP Receptor Binding Affinity of 25 and 36a.
| compd | EP1 (μM) | EP2 (μM) | EP3 (μM) | EP4 (nM) |
|---|---|---|---|---|
| 25 | >9.6 | >8.8 | >6.4 | 143.9 ± 55.8 |
| 36 | >9.6 | >8.8 | >6.4 | 65.9 ± 20.4 |
Data (Ki values) are presented as the mean ± standard error of three independent experiments.
| compd | EP1 (μM) | EP2 (μM) | EP3 (μM) | EP4 (nM) |
|---|---|---|---|---|
| 25 | >9.6 | >8.8 | >6.4 | 143.9 ± 55.8 |
| 36 | >9.6 | >8.8 | >6.4 | 65.9 ± 20.4 |
Data (Ki values) are presented as the mean ± standard error of three independent experiments.