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. 2023 May 10;14(6):846–852. doi: 10.1021/acsmedchemlett.3c00114

Table 3. Extended Substrate Scope 3a.

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a

Reaction conditions: substrate (50 mg), water (35 mL), EtOH (1 mL), pH 8.5 buffer (0.7 mL), pre-cut purple carrots (10 g), in an Erlenmeyer flask, stirred at 250 rpm. The er was determined by chiral SFC or HPLC. For compound 46: 1 g scale, 69% yield, 97:3 er.