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. Author manuscript; available in PMC: 2023 Jun 12.
Published in final edited form as: Sci Transl Med. 2023 May 3;15(694):eadg5562. doi: 10.1126/scitranslmed.adg5562

Fig. 1. The abundance of potential pathogens increases in stool of NICU infants after antibiotics.

Fig. 1.

Family-level changes of bacteria in the gut microbiome were assessed regarding receipt of ampicillin, gentamicin, or vancomycin in the prior 10 days for previously sequenced infants in the cohort irrespective of BSI status. (A) Enterobacteriaceae and (B) Enterococcaceae were the only families found to be changed in the gut after either or both ampicillin and gentamicin. Recent vancomycin or gentamicin increased Enterococcaceae (C) but decreased Enterobacteriaceae (D) abundance, as assessed by MaAsLin2 with DOL as an additional fixed effect and participant as random effect. All P < 0.05 by generalized LME model, q value is Benjamini-Hochberg–corrected for multiple comparisons.