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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Matrix Biol. 2023 Mar 11;118:92–109. doi: 10.1016/j.matbio.2023.03.005

Figure 4. Differential transcriptomic landscape of endorepellin expression in vasculature of E0771 breast allografts.

Figure 4.

(A) Heat map and (B) volcano plot displays of differentially expressed genes from Tie2CreERT2;ERKi allografts treated with tamoxifen vs control using RNAseq analysis. Applying parameters of >2-fold change and a p<0.05 resulted in 58 upregulated genes and 294 downregulated genes. (C) Real time qPCR analysis of gene targets from both up- and down-regulated gene datasets confirmed RNAseq findings (blue for vehicle, red for tamoxifen). Statistical analyses were calculated via two-tailed Student’s t test (*p <0.05).