Table A3.
Joint association between current occupation category and self-reported working conditions in 2010 and epigenetic age measures.
| PCHorvath |
PCHannum |
PCPhenoAge |
PCGrimAge |
DunedinPACE |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M1 | M2 | M3 | M1 | M2 | M3 | M1 | M2 | M3 | M1 | M2 | M3 | M1 | M2 | M3 | |
| Managerial/ Professional (reference) |
|||||||||||||||
| Sales/ Clerical |
1.036** | 0.813* | 0.789* | 1.298** | 1.078* | 1.079** | 1.57*** | 0.731+ | 0.736+ | 0.948*** | 0.334 | 0.300 | 0.033** | 0.008 | 0.007 |
| p-value | 0.005 | 0.034 | 0.039 | 0.001 | 0.010 | 0.009 | <0.001 | 0.090 | 0.074 | <0.001 | 0.214 | 0.192 | 0.001 | 0.424 | 0.446 |
| Service | 0.439 | 0.677 | 0.449 | 0.781 | 0.867+ | 0.62 | 2.489*** | 1.209* | 0.831 | 1.626*** | 0.968** | 0.659* | 0.049*** | 0.001 | −0.006 |
| p-value | 0.332 | 0.158 | 0.346 | 0.109 | 0.096 | 0.230 | <0.001 | 0.025 | 0.105 | <0.001 | 0.004 | 0.020 | <0.001 | 0.951 | 0.636 |
| Manual | 0.335 | −0.013 | −0.079 | 0.33 | −0.034 | 0.000 | 1.963*** | 0.678 | 0.678 | 2.087*** | 1.166*** | 0.440 | 0.052*** | 0.008 | −0.002 |
| p-value | 0.443 | 0.978 | 0.868 | 0.484 | 0.947 | 1.000 | <0.001 | 0.204 | 0.188 | <0.001 | <0.001 | 0.124 | <0.001 | 0.522 | 0.899 |
| High stress | −0.089 | −0.249 | −0.374 | −0.166 | −0.279 | −0.386 | 0.075 | 0.127 | −0.130 | 0.744** | 0.691** | 0.235 | 0.02* | 0.023* | 0.009 |
| p-value | 0.804 | 0.479 | 0.288 | 0.669 | 0.467 | 0.313 | 0.852 | 0.749 | 0.730 | 0.003 | 0.005 | 0.258 | 0.049 | 0.015 | 0.336 |
| High physical effort | −0.013 | 0.094 | 0.18 | 0.403 | 0.467 | 0.55 | −0.177 | −0.548 | −0.448 | 0.009 | −0.171 | −0.126 | 0.013 | 0.000 | −0.001 |
| p-value | 0.975 | 0.813 | 0.647 | 0.352 | 0.280 | 0.196 | 0.693 | 0.216 | 0.287 | 0.974 | 0.535 | 0.585 | 0.253 | 0.981 | 0.891 |
| Long working hours | 0.335 | 0.161 | 0.152 | 0.35 | 0.222 | 0.189 | −0.039 | 0.181 | 0.185 | 0.516 | 0.572+ | 0.251 | 0.001 | 0.009 | 0.002 |
| p-value | 0.490 | 0.736 | 0.751 | 0.506 | 0.673 | 0.716 | 0.943 | 0.734 | 0.717 | 0.125 | 0.084 | 0.379 | 0.923 | 0.480 | 0.858 |
| Controls for age & sex? | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
| Race & education? | X | X | X | X | X | X | X | X | X | X | |||||
| Health behaviours in 2016? | X | X | X | X | X | ||||||||||
| R-squared | 0.242 | 0.277 | 0.301 | 0.249 | 0.267 | 0.298 | 0.301 | 0.335 | 0.408 | 0.475 | 0.499 | 0.646 | 0.040 | 0.124 | 0.260 |
| AIC | 8,042 | 7,994 | 7,969 | 8,224 | 8,205 | 8,168 | 8,330 | 8,280 | 8,149 | 7,125 | 7,078 | 6,660 | −947 | −1,049 | −1,244 |
| N | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 | 1,251 |
+p < 0.10, * p < 0.05, ** p < 0.01, *** p <0.001. Results are pooled across 10 imputations. Model 1 adjusts for age and sex. Model 2 additionally includes race/ethnicity and educational attainment. Model 3 additionally includes smoking status, alcohol consumption, physical inactivity, and Body Mass Index (BMI) category.