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. 2022 Feb 7;2(1):1–8. doi: 10.1530/EO-21-0021

Table 1.

Clinical characteristics of the entire cohort of patients with ACC (n  = 45) and patient subgroup with a complete lipid profile before and after the introduction of mitotane (n  = 26). Data for continuous variables are expressed as median ± s.d. Categorical variables are expressed as frequency (n (%)).

Variables n= 26 n= 45
Age (years) 50 ± 13 50 ± 14
Sex
 Male 6 (23%) 10 (22%)
 Female 20 (77%) 35 (78%)
ENSAT stage
 I 0 (0%) 2 (4%)
 II 9 (35%) 11 (24%)
 III 11 (42%) 15 (33%)
 IV 6 (23%) 17 (38%)
Median tumor diameter (cm) 11,58 (2.5–21.5) 11,38 (2.5–24)
Median Weiss score 6 (n  = 16) (3–9) 6 (n  = 26) (3–9)
Functional status
 Secreting tumors 16 (62%) 29 (64%)
  • Glucocorticoids only

  • Aldosterone only

  • Androgens only

  • Glucocorticoids and androgens

5
3
2
6
10
4
2
13
 Non-secreting tumors 3 (11%) 5 (11%)
 Unknown 7 (27%) 11 (25%)
Concomitant treatments
Cytotoxic chemotherapy 9 (35%) 20 (44%)
Past medical history of treated dyslipidemia
 Yes 6 (23%) 10 (22%)
 No 20 (77%) 34 (76%)