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. 2023 Jun 6;16(6):dmm049531. doi: 10.1242/dmm.049531

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© 2023. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 7. — Power Doppler analysis of tumours treated with fXRT and/or USMB. (A) Maximum-intensity projections of power Doppler (PD) signals within a 3D volumetric tumour scan of whole tumours undergoing the indicated treatments. The colour bar represents a range from 11 dB (black) to 30 dB (orange). Scale bar: 1 cm. (B-D) Percentage change of the vascular index signal in each treatment condition for the WT, S1P-treated and ASMase^−/− groups. Each cohort had five mice. Results are represented as signal intensity change from baseline pre-treatment scan. Error bars represent mean±s.e.m. Statistical analysis by Welch's two-tailed unpaired t-test. *P<0.05.