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. 2023 Jun 12;55(6):1066–1075. doi: 10.1038/s41588-023-01421-y

Extended Data Fig. 6. eQTL and disease GWAS colocalisation.

Extended Data Fig. 6

a. ATF6 expression on the UMAP of fibroblast data. UMAP coordinates are identical to Fig. 2a. b. ATF motif (M6155_1.02; CIS-BP version 1.02). The nucleotide C coloured by red indicates the location of the eQTL variant rs1998266T>C. c. Locus zoom plots of hayfever, allergic rhinitis or eczema, rheumatoid arthritis and the ETV7 eQTL. d. The numbers of colocalised loci between our eQTLs and OpenTarges GWAS traits that were overlapping with the OpenTarges colocalisation resource for GTEx eQTLs (48 tissues) as well as monocytes and iPSC derived macrophages under various stimulation conditions.