Table 2.
Comparison of the percentage of thyroid-stimulating hormone (TSH) concentration >5 mIU/l and median TSH concentration of newborns by potential time-varying confounders, 2005–2016, South Australia (n 211 033)
| Variable | % of TSH > 5 mIU/l* | P value† | TSH (mIU/l) | P value‡xs | ||
|---|---|---|---|---|---|---|
| n | % | Median | IQR | |||
| Neonatal age | < 0·01 | < 0·01 | ||||
| 48–72 h | 9799 | 5·1 | 1·9 | 1·2, 2·9 | ||
| 72–96 h | 584 | 2·9 | 1·6 | 1·0, 2·4 | ||
| Sex | < 0·01 | < 0·01 | ||||
| Male | 1451§ | 4·8 | 1·8 | 1·1, 2·7 | ||
| Female | 1065§ | 3·7 | 1·6 | 1·0, 2·5 | ||
| Birth weight | < 0·01 | < 0·01 | ||||
| >2500 g | 9345 | 4·8 | 1·9 | 1·2, 2·8 | ||
| ≤2500 g | 1308 | 7·0 | 2·0 | 1·3, 3·1 | ||
| Gestational age | 0·01 | 0·73 | ||||
| ≥37 weeks | 5704║ | 5·0 | 2·0 | 1·3, 2·9 | ||
| <37 weeks | 1282║ | 5·5 | 2·0 | 1·3, 2·9 | ||
| Season | < 0·01 | < 0·01 | ||||
| Summer | 2475 | 4·8 | 1·9 | 1·2, 2·8 | ||
| Autumn | 2512 | 4·7 | 1·8 | 1·2, 2·8 | ||
| Winter | 2741 | 5·2 | 1·9 | 1·2, 2·9 | ||
| Spring | 2655 | 5·0 | 2·0 | 1·3, 2·9 | ||
n, number of samples; IQR, interquartile range.
*
Denominator was n 211 033 unless otherwise specified.
†
P values were from the χ2 test.
‡
P values were from the Kruskal–Wallis test.
§
Denominator was n 58 858.
║
Denominator was n 136 958.