Table 4.
Quality assessment of iodine status measurements of relevant studies on iodine deficiency among women in the UK
| Bath et al. (2013)( 19 ) | Bath et al. (2014)( 13 ) | Bath et al. (2014)( 14 ) * | Bath et al. (2015)( 16 ) | Combet and Lean (2014)( 15 ) * | Combet et al. (2015)( 36 ) | Kibirige et al. (2004)( 23 ) | Knight et al. (2017)( 17 ) | O’Kane et al. (2016)( 34 ) * | Pearce et al. (2010)( 18 ) | Vanderpump et al. (2011)( 8 ) * | Derbyshire et al. (2009)( 37 ) | NDNS (2018)( 20 ) * | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Spot urinary sample collection | Y | Y | N | Y | N | N | Y | Y | N | Y | Y | N | Y |
| 24 h Urinary sample collection | N | N | Y | N | Y | N | N | N | N | N | N | N | N |
| UIC corrected by creatinine concentration | Y | Y | N | Y | Y | N | Y | N | N | N | N | N | N |
| Adequate sample size | Y | Y | N | Y | N | Y | Y | Y | Y | Y | Y | N | Y |
| Preassessment of thyroid disease | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | N | Y | Y |
| Nationally representative | N | N | N | N | N | Y | N | N | Y | N | Y | N | Y |
| Reduced seasonal bias | Y | N | N | Y | N | Y | N | Y | N | N | Y | N | Y |
| No contaminated urine sample | N | Y | Y | Y | Y | NA | Y | Y | NA | N | Y | NA | Y |
| Overall quality rating | Good | Good | Fair | Good | Fair | Poor | Poor† | Fair | Poor | Poor | Fair | Poor | Good |
NDNS, National Diet and Nutrition Survey; UIC, urinary iodine concentration; Y, yes; N, no; NA, not available.
*
Study in non-pregnant/non-lactating women.
†
The inappropriate data reporting in Kibirige et al.’s study( 23 ) suggests a poor quality of iodine assessment design.