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. 2023 Jan 5;3(3):243–254. doi: 10.1007/s43657-022-00087-6

Table 1.

Comparisons of the performance for prediction of glioma grades and molecular subtypes on different MR modalities by fivefold cross-validation of deep learning

Tasks Modality Accuracy Sensitivity Specificity PPV NPV F1-score
OGG/GBM T2 FLAIR 0.69 ± 0.11 0.75 ± 0.22 0.60 ± 0.25 0.75 ± 0.14 0.65 ± 0.18 0.60 ± 0.12
T1WI + C 0.74 ± 0.11 0.75 ± 0.22 0.73 ± 0.25 0.83 ± 0.15 0.64 ± 0.08 0.70 ± 0.14
QSM 0.80 ± 0.07 0.86 ± 0.12 0.73 ± 0.25 0.84 ± 0.13 0.75 ± 0.13 0.75 ± 0.14
LGG/HGG T2 FLAIR 0.69 ± 0.11 0.80 ± 0.19 0.53 ± 0.16 0.70 ± 0.07 0.67 ± 0.18 0.61 ± 0.13
T1WI + C 0.74 ± 0.14 0.76 ± 0.16 0.73 ± 0.25 0.81 ± 0.17 0.62 ± 0.10 0.72 ± 0.17
QSM 0.69 ± 0.11 0.70 ± 0.19 0.67 ± 0.21 0.76 ± 0.14 0.59 ± 0.08 0.64 ± 0.12
IDH1(+)/(−) T2 FLAIR 0.57 ± 0.20 0.65 ± 0.26 0.47 ± 0.16 0.60 ± 0.17 0.48 ± 0.17 0.53 ± 0.19
T1WI + C 0.57 ± 0.20 0.60 ± 0.26 0.53 ± 0.27 0.63 ± 0.22 0.57 ± 0.28 0.52 ± 0.19
QSM 0.77 ± 0.11 0.86 ± 0.12 0.67 ± 0.30 0.81 ± 0.17 0.72 ± 0.16 0.70 ± 0.18
ATRX(−)/(+) T2 FLAIR 0.54 ± 0.17 0.60 ± 0.26 0.47 ± 0.27 0.62 ± 0.22 0.54 ± 0.26 0.46 ± 0.13
T1WI + C 0.46 ± 0.11 0.50 ± 0.16 0.40 ± 0.13 0.52 ± 0.11 0.38 ± 0.10 0.42 ± 0.09
QSM 0.60 ± 0.11 0.65 ± 0.20 0.53 ± 0.27 0.69 ± 0.17 0.59 ± 0.22 0.52 ± 0.09

OGG other grade glioma (grade II + III), GBM glioblastoma multiforme (grade IV), LGG low-grade glioma (grade II), HGG high-grade glioma (grade III + IV), IDH1(+) IDH1 mutation, IDH1(−) IDH1 wild, ATRX(−) ATRX expression loss, ATRX(+) ATRX retention, PPV positive predictive value, NPV negative predictive value

The best results are marked in bold