Fig. 1. Methods for the selective transformation of less reactive carbonyl compounds.

a Reactivity order of carbonyl compounds²⁷. b Indirect synthetic approaches by protection-deprotection strategy. c Amide-selective catalytic reduction using hydrosilanes or dihydrogen. d Catalytic hydrogenolysis of urea functionality into methanol and two molecules of amines. e Chemoselective hydrogenolysis of urea derivatives into formamides and amines and unprecedented reactivity order of carbonyl compounds (This work).