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. 2023 May 7;146(1):77–95. doi: 10.1007/s00401-023-02583-z

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Module-trait correlations for the FTLD co-methylation networks. a FTLD1; b FTLD2; c FTLD3. The rows represent the co-methylation module eigengenes (ME) and their colours, and the column represents the correlation of the methylation levels of CpGs in each module with the disease status. p-values are presented within each cell and the colour scale at the right indicates the strength of the correlation (darker cells depict stronger correlations, with blue representing negative and red representing positive correlations)