Table 3.

Plasma p-tau in the association of brain β-amyloid with PHFtau tangles

Plasma ptau-181						Plasma ptau-217
Path			Estimate	SE	p	Path			Estimate	SE	p
Tangles	←	Age	0.042	0.063	0.505	Tangles	←	Age	0.033	0.059	0.579
Tangles	←	Male sex	− 0.077	0.063	0.226	Tangles	←	Male sex	− 0.069	0.059	0.240
Tangles	←	Education	0.003	0.064	0.959	Tangles	←	Education	− 0.0003	0.059	0.997
Tangles	←	ptau-181	0.325	0.066	< .001	Tangles	←	ptau-217	0.524	0.063	< .001
Tangles	←	β-amyloid	0.225	0.067	< .001	Tangles	←	β-amyloid	0.066	0.069	0.340
β-amyloid	←	Age	0.004	0.071	0.950	β-amyloid	←	Age	0.004	0.071	0.950
β-amyloid	←	Male sex	0.065	0.071	0.359	β-amyloid	←	Male sex	0.065	0.071	0.359
β-amyloid	←	Education	0.049	0.071	0.489	β-amyloid	←	Education	0.049	0.071	0.489
ptau-181	←	Age	0.076	0.065	0.243	ptau-217	←	Age	0.065	0.060	0.274
ptau-181	←	Male sex	− 0.049	0.066	0.459	ptau-217	←	Male sex	− 0.044	0.060	0.461
ptau-181	←	Education	0.102	0.065	0.117	ptau-217	←	Education	0.070	0.060	0.241
ptau-181	←	β-amyloid	0.375	0.061	< .001	ptau-217	←	β-amyloid	0.536	0.051	< .001