Table 4.
Soluble transferrin receptor (TfR) concentrations, ratios with 95 % confidence intervals and correction factors (CF) by inflammatory status in Senegalese schoolchildren, Cambodian schoolchildren and Cambodian women of reproductive age (WRA)
| TfR (mg/l)† | ||||||||
|---|---|---|---|---|---|---|---|---|
| n | % | Mean | sd | P value‡ | Ratio§ | 95 % CI | CF║ | |
| All subjects combined | ||||||||
| No inflammation | 3817 | 74 | 6·8 | 1·4 | – | – | – | |
| Incubation | 98 | 2 | 5·8 | 1·3 | 0·000 | 0·85 | 0·81, 0·89 | 1·17 |
| Early convalescence | 219 | 4 | 7·8 | 1·4 | 0·000 | 1·16 | 1·12, 1·18 | 0·87 |
| Late convalescence | 1048 | 20 | 8·7 | 1·3 | 0·000 | 1·29 | 1·27, 1·29 | 0·78 |
| Senegalese schoolchildren | ||||||||
| No inflammation | 522 | 88 | 7·7 | 1·3 | – | – | – | |
| Incubation | 9 | 2 | 7·5 | 7·7 | 0·746 | 0·97 | 0·32, 1·63 | 1·03 |
| Early convalescence | 25 | 4 | 8·2 | 1·3 | 0·266 | 1·07 | 1·00, 1·13 | 0·94 |
| Late convalescence | 38 | 6 | 7·9 | 1·2 | 0·653 | 1·02 | 0·97, 1·08 | 0·98 |
| Cambodian schoolchildren | ||||||||
| No inflammation | 1476 | 60 | 8·0 | 1·3 | – | – | – | |
| Incubation | 9 | 0 | 7·2 | 1·3 | 0·206 | 0·90 | 0·79, 1·01 | 1·12 |
| Early convalescence | 130 | 5 | 8·8 | 1·3 | 0·000 | 1·10 | 1·07, 1·13 | 0·91 |
| Late convalescence | 856 | 35 | 9·3 | 1·3 | 0·000 | 1·15 | 1·15, 1·18 | 0·87 |
| Cambodian WRA | ||||||||
| No inflammation | 1819 | 86 | 5·7 | 1·4 | – | – | – | |
| Incubation | 80 | 4 | 5·5 | 1·3 | 0·296 | 0·96 | 0·91, 1·02 | 1·04 |
| Early convalescence | 64 | 3 | 6·0 | 1·4 | 0·145 | 1·06 | 0·99, 1·11 | 0·94 |
| Late convalescence | 154 | 7 | 6·4 | 1·4 | 0·000 | 1·13 | 1·08, 1·16 | 0·89 |
| All subjects combined | ||||||||
| Normal AGP | 3915 | 76 | 6·8 | 1·4 | – | – | – | |
| High AGP | 1267 | 24 | 8·6 | 1·4 | 0·000 | 1·27 | 1·25, 1·28 | 0·79 |
| Senegalese schoolchildren | ||||||||
| Normal AGP | 531 | 89 | 7·7 | 1·3 | – | – | – | |
| High AGP | 63 | 11 | 8·0 | 1·3 | 0·301 | 1·04 | 0·99, 1·08 | 0·96 |
| Cambodian schoolchildren | ||||||||
| Normal AGP | 1485 | 60 | 8·0 | 1·3 | – | – | – | |
| High AGP | 986 | 40 | 9·2 | 1·3 | 0·000 | 1·15 | 1·14, 1·16 | 0·87 |
| Cambodian WRA | ||||||||
| Normal AGP | 1899 | 90 | 5·7 | 1·4 | – | – | – | |
| High AGP | 218 | 10 | 6·3 | 1·4 | 0·000 | 1·11 | 1·07, 1·14 | 0·90 |
| All subjects combined | ||||||||
| Normal CRP | 4865 | 94 | 7·2 | 1·4 | – | – | – | |
| High CRP | 317 | 6 | 7·1 | 1·4 | 0·847 | 1·00 | 0·96, 1·01 | 1·00 |
| Senegalese schoolchildren | ||||||||
| Normal CRP | 560 | 94 | 7·7 | 1·3 | – | – | – | |
| High CRP | 34 | 6 | 8·0 | 1·3 | 0·449 | 1·04 | 0·98, 1·10 | 0·96 |
| Cambodian schoolchildren | ||||||||
| Normal CRP | 2332 | 94 | 8·5 | 1·3 | – | – | – | |
| High CRP | 139 | 6 | 8·7 | 1·3 | 0·238 | 1·03 | 1·00, 1·05 | 0·97 |
| Cambodian WRA | ||||||||
| Normal CRP | 1973 | 93 | 5·7 | 1·4 | – | – | – | |
| High CRP | 144 | 7 | 5·7 | 1·4 | 0·170 | 1·00 | 0·96, 1·04 | 1·00 |
AGP, α1-acid glycoprotein; CRP, C-reactive protein.
†
Geometric means and sd.
‡
ANOVA on log-transformed TfR means of positive group v. control group.
§
Ratio of back-transformed TfR concentrations of positive group v. control group.
║
CF=1/ratio.