Table 3C:

Spearman correlations between abundance of selected gut microbiota and early Sjogren’s Syndrome markers among cases

	SP1 IgG	SP1 IgA	SP1 IgM	PSP IgG	PSP IgA	PSP IgM	CA6 IgG	CA6 IgA	CA6 IgM
Genus
Veillonella
rho=	−0.34	−0.20	−0.14	0.07	0.10	0.20	−0.12	0.11	0.21
p=	0.15	0.41	1.0	0.79	0.68	0.41	0.64	0.65	0.38
Species
Lactobacillus salivarius
rho=	−0.39	−0.19	−0.46	0.10	−0.13	0.07	−0.25	0.16	−0.07
p=	0.10	0.44	0.048*	0.69	0.59	0.79	0.30	0.53	0.76
Bifidobacterium animalis
rho=	−0.16	−0.03	0.09	0.04	0.33	0.34	−0.03	0.33	0.30
p=	0.52	0.91	0.71	0.89	0.17	0.15	0.91	0.17	0.22
Prevotella stercorea
rho=	0.32	−0.11	0.05	−0.04	0.14	0.03	−0.12	0.19	0.32
p=	0.19	0.65	0.84	0.88	0.56	0.89	0.66	0.45	0.19
Fusobacterium varium
rho=	0.26	−0.29	−0.52	0.26	−0.05	0.27	−0.44	0.14	−0.20
p=	0.29	0.24	0.02*	0.28	0.85	0.27	0.06	0.58	0.41

Abbreviation: SP1, salivary protein 1, PSP, parotid secretary protein, CA6, carbonic anhydrase 6, Ig, immunoglobulin

^*p < 0.05,

^**p < 0.01,

^***p < 0.001