Table 3.
Association of 25-hydroxyvitamin D (25(OH)D) with insulin resistance, SPECT-China 2014 study
| 25(OH)D (nmol/l) | ||||||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | ||||
| Dependent variable | Standardized coefficient | se | Standardized coefficient | se | Standardized coefficient | se |
| Log10HOMA-IR (total sample) | −0·058*** | 0·000 | −0·050*** | 0·000 | −0·038** | 0·000 |
| Subgroup analyses by glucose status | ||||||
| Log10HOMA-IR (NGT) | −0·037* | 0·001 | −0·024 | 0·000 | −0·025 | 0·000 |
| Log10HOMA-IR (pre-diabetes) | −0·160*** | 0·001 | −0·120*** | 0·001 | −0·061* | 0·001 |
| Log10HOMA-IR (diabetes) | −0·117*** | 0·001 | −0·083 | 0·001 | −0·058 | 0·001 |
| Subgroup analyses by weight | ||||||
| Log10HOMA-IR (normal weight) | −0·047** | 0·000 | −0·022 | 0·000 | −0·027 | 0·000 |
| Log10HOMA-IR (overweight) | −0·081*** | 0·001 | −0·071** | 0·001 | −0·061** | 0·001 |
| Log10HOMA-IR (obesity) | −0·120* | 0·002 | −0·107 | 0·002 | −0·058 | 0·002 |
| Subgroup analyses by season | ||||||
| Log10HOMA-IR (winter) | −0·079*** | 0·000 | −0·063** | 0·000 | −0·065** | 0·000 |
| Log10HOMA-IR (spring) | −0·036* | 0·001 | −0·039* | 0·001 | −0·008 | 0·000 |
SPECT-China 2014, Survey on the Prevalence in East China of Metabolic Diseases and Risk Factors, 2014; HOMA-IR, homeostasis model assessment of insulin resistance; NGT, normal glucose tolerance; HbA1c, glycated Hb.
Linear regression analyses were used.
Model 1 was unadjusted. Model 2 included terms for age, sex, smoking, drinking. Model 3 included terms for model 2, HbA1c (not in subgroup analyses by glucose status), BMI (not in subgroup analyses by weight) and season (not in subgroup analyses by season).
*P<0·05, **P<0·01, ***P<0·001.