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. 2023 May 9;12(5):971–984. doi: 10.21037/tlcr-22-818

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2023 Translational Lung Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Dynamics in the number of mutant molecules per mL plasma. (A,B) Kaplan-Meier survival analysis according to change in ctDNA with a threshold of 50% for change. (C,D) Kaplan-Meier survival analysis for patients experiencing any increase in ctDNA. OS, overall survival; PFS, progression-free survival.