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. 2023 May 29;12(5):1093–1107. doi: 10.21037/tlcr-23-258

Figure 5.

Figure 5

RT may upregulate C5aR through AKT/NF-κB pathway. (A,B) Western blotting exhibited that RT upregulated the activation of the AKT/NF-κB pathway and expression of C5aR. (C) qRT-PCR analysis of TNF-α, IL-6, and IL-12 mRNA levels in the tumor tissues of mice from RT and control groups (n=3). *, P<0.05. GAPDH, glyceraldehyde 3-phosphate dehydrogenase; RT, radiotherapy; mRNA, messenger RNA; qRT-PCR, quantitative real-time polymerase chain reaction; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; IL-12, interleukin-12.