Figure 6.
Population change in fibrosis score over 12 months. (A) For each stage of fibrosis, the average predicted percent of the population that improved (green bars), declined (red bars), or stayed the same (black bars). (B) The predicted percentage of patients with improvement in fibrosis score of 1 or more vs. the number of patients in the study for a typical patient cohort. The percentage of patients improved from Cusi et al. extracted from [Appendix, (21)], Belfort et al. extracted from p. 2305, and Aithal et al. extracted from p. 1179 (21–23) is overlaid with model simulations. (C) The predicted percentage of patients with improvement in fibrosis score of 1 or more vs. the number of patients in the study for a cohort with 50% F2 and 50% F3 patients. Error bars represent the 90th percentile.