Oxidation of 1-phenylethanol with complex 1 and 2a.
| ||||||
|---|---|---|---|---|---|---|
| Entry | Complex | Temperature (°C) | TOFmax (h−1) | Conversion (yield)b % | ||
| 30 min | 1 h | 8 h | ||||
| 1 | 1 | 80 | 500 | 55 (52) | 60 (58) | 69 (67) |
| 2 | 2 | 80 | 540 | 62 (60) | 70 (67) | 80 (79) |
| 3 | 1 | 60 | 280 | 53 (51) | 66 (63) | 81 (79) |
| 4 | 2 | 60 | 290 | 54 (53) | 66 (63) | 94 (93) |
| 5 | 2 | 50 | 130 | 35 (33) | 54 (53) | 89 (86) |
| 6 | 2 | 40 | 97 | 21 (20) | 32 (30) | 84 (82) |
| 7 | 2 | 25 | 39 | 6 (6) | 10 (9) | 24 (22) |
| 8 | Mn(acac)3 | 60 | 61 | 17 (16) | 23 (21) | 69 (65) |
| 9 | — | 60 | — | 7 (7) | 10 (8) | 20 (18) |
a
Reaction conditions: 0.5 mmol substrate, 0.75 mmol TBHP, 1 mol% Mn complex, 0.06 mmol 1,3,5-trimethoxybenzene, 0.6 mL MeCN, 8 h.
b
Determined by GC-FID analysis using 1,3,5-trimethoxybenzene as internal standard.