Table 1.

The shape-function independence ratio κ for selected keywords, with confidence intervals (CI) estimated from bootstrap resamples and P-values estimated from permutation tests

Keyword	κ	95 % CI	P-value
Kinase	0.97	0.74 1.04	0.79
Calcium	0.89	0.86 1.08	0.60
DNA-binding	1.83	1.67 1.99	7.1 × ${10}^{-14}$
Zinc-finger	2.48	2.05 2.88	5.5 × ${10}^{-14}$