Table 1. Particle Size of Silybin Suspensions after High-Pressure Homogenization and Ball Milling.

pretreatment method	particle size (nm)	PDI
homogen 0 cycles	1397.7 ± 214.0	0.994
homogen 4 cycles	705.5 ± 66.8	0.385
homogen 8 cycles	600.9 ± 53.6	0.143
homogen 12 cycles	552.5 ± 40.9	0.209
ball-milling 0 h	1147.3 ± 175.1	0.932
ball-milling 1 h	362.4 ± 10.1	0.403
ball-milling 2 h	355.6 ± 4.1	0.343
ball-milling 3 h	318.9 ± 4.0	0.293