Table 2.

Intraoperative profiles

	Liberal fluid infusion group (PPV target 6–9%) (n=48)	Restrictive fluid infusion group (PPV target 13–16%) (n=49)
Anaesthesia time (min)	181±29	178±23
Operation time (min)	139±27	135±22
Prone time (min)	154±28	149±23
End-tidal sevoflurane concentration (%)	2.0±0.3	1.9±0.4
Fluid infusion
Baseline (ml)	211±40	203±38
Number of boluses (n)	7±2	5±2^^^
Total bolus volume (ml)	1747±517	1099±395^^^
Blood loss (ml)	150±67	162±70
Urine output (ml)	302±163	163±63 ^^^
Body temperature (°C)	36.5±0.2	36.5±0.3
PPV (%)
Baseline	14±2	15±2
Intraoperative time-weighted average	8±1***	14±1^^^
Haematocrit (%)
Baseline before anaesthesia	39.9±1.1	40.2±1.6
During anaesthesia
1 h	36.2±1.0***	37.1±1.2***^
2 h	35.6±1.1***	36.9±1.1***^^
End of surgery	35.4±1.3***	36.8±1.1***^^
PaO2 (mmHg)
Baseline before anaesthesia	85.1±9.7	85.9±11.2
During anaesthesia
1 h	297.1±63.4***	297.6±55.9***
2 h	294.4±61.9***	300.8±49.8***
End of surgery	290.5±60.2***	292.8±46.4***
PaCO2 (mmHg)
Baseline before anaesthesia	36.3±2.4	36.1±2.4
During anaesthesia
1 h	36.9±2.4	37.3±1.5**
2 h	37.0±2.0	36.6±1.1
End of surgery	37.2±1.3 **	36.3±1.4
Lactate (mmol•L–1)
Baseline before anaesthesia	0.9±0.2	0.8±0.3
During anaesthesia
1 h	1.2±0.2***	1.1±0.3***
2 h	1.2±0.2***	1.1±0.3***
End of surgery	1.2±0.2***	1.1±0.3***
Patients needed vasopressors (n)	39	40
Total ephedrine dose (mg)	3±4	3±3
Total phenylephrine dose (μg)	29±36	36±39

Data are presented as mean±standard deviation or n (proportion)

PPV pulse pressure variation

^*p<0.05 compared to baseline, **p<0.01 compared to baseline, ***p<0.001 compared to baseline

^p<0.05 compared to the liberal fluid infusion group, ^^p<0.01 compared to the liberal fluid infusion group, ^^^p<0.001 compared to the liberal fluid infusion group