Fig. 6.

Hcy induced ER stress response of macrophages. A Western blot was used to evaluate the ERS-related proteins (p-PERK, p-eif2α, ATF4, CHOP) level after Hcy treated. B–E Relative protein expressions quantification of ERS-related proteins. F Western blot was used to evaluate the pyroptosis-related proteins level after ERS inhibitor 4PBA pretreatment. G–M Relative protein expressions quantification of ERS-related and pyroptosis-associated proteins. The data are shown as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001