Fig. 5.

Stimulation of human pancreatic ductal cells with EZH2 inhibitors GSK-126 at 10 µM, EPZ6438 at 1 µM and triptolide at 20 nM influences the expression of insulin (INS) following A 2-day and B 7-day stimulation. Images were captured using ThermoFisher EVOS at 40×magnification and processed on ImageJ. Images are representative of 3 replicates. Scale bar represents 50 µM. White arrows indicate INS expressing CK19-positive cells