Table 4.
Comparison of dynamic contrast-enhanced magnetic resonance imaging qualitative and quantitative parameters in prostate cancer lesions based on Prostate Imaging–Reporting and Data System version 2
| Overall | Index | Peripheral | Transition | ≥ 1 cm | < 1 cm | |
|---|---|---|---|---|---|---|
|
| ||||||
| Ktrans [median (Q1–Q3a)] | p < 0.001* | p = 0.074 | p < 0.001* | p = 0.645 | p < 0.001* | p = 0.652 |
| 3 | 0.34 (0.22–0.58) | 0.41 (0.21–0.58) | 0.32 (0.21–0.56) | 0.37 (0.24–0.7) | 0.34 (0.22–0.61) | 0.32 (0.22–0.51) |
| 4 | 0.39 (0.29–0.64) | 0.27 (0.29–0.63) | 0.4 (0.29–0.66) | 0.35 (0.29–0.52) | 0.4 (0.29–0.64) | 0.30 (0.16–0.51) |
| 5 | 0.51 (0.31–0.80) | 0.72 (0.32–0.81) | 0.53 (0.32–0.81) | 0.45 (0.3–0.8) | 0.52 (0.31–0.8) | 1.03b |
| Kep [median (Q1–Q3)] | p = 0.004* | p < 0.001* | p = 0.002* | p = 0.486 | p = 0.002* | p = 0.577 |
| 3 | 1.29 (0.79–2.06) | 1.17 (0.78–1.86) | 1.26 (0.78–2.06) | 1.33 (0.83–2.11) | 1.25 (0.8–1.92) | 1.36 (0.8–2.1) |
| 4 | 1.49 (1.08–2.28) | 1.51 (1.12–2.1) | 1.56 (1.12–2.53) | 1.22 (0.86–1.64) | 1.49 (1.12–2.2) | 1.58 (0.84–2.7) |
| 5 | 1.75 (1.19–2.98) | 1.79 (1.17–2.98) | 1.81 (1.17–3.13) | 1.67 (1.2–2.74) | 1.77 (1.17–2.98) | 4.54b |
| iAUC [median (Q1–Q3)] | p = 0.002* | p < 0.001* | p = 0.001* | p = 0.548 | p = 0.008* | p = 0.770 |
| 3 | 7.60 (5.12–10.7) | 8.45 (4.84–10.8) | 7.34 (5–10.15) | 8.34 (6.21–13.06) | 7.76 (5.12–11) | 7.2 (5.21–9.38) |
| 4 | 8.54 (6.52–11.35) | 7.10 (6.75–11.7) | 8.71 (6.4–11.7) | 7.83 (6.8–11.11) | 8.68 (6.55–11.47) | 6.8 (4.7–8.98) |
| 5 | 9.79 (7.21–12.9) | 11.3 (7.24–12.93) | 9.83 (7.02–12.93) | 9.74 (7.6–11.39) | 9.82 (7.02–12.93) | 10.98b |
| Curve type | p < 0.001* | p = 0.002* | p = 0.003* | p = 0.060 | p < 0.001* | p = 0.350 |
| 3 | 106 | 64 | 71 | 35 | 82 | 24 |
| Type 1 | 7 (6.6%) | 5 (7.8%) | 6 (8.5%) | 1 (2.9%) | 7 (8.5%) | 0 (0%) |
| Type 2 | 44 (41.5%) | 24 (37.5%) | 28 (39.4%) | 16 (45.7%) | 32 (39%) | 12 (50%) |
| Type 3 | 55 (51.9%) | 35 (54.7%) | 37 (52.1%) | 18 (51.4%) | 43 (52.4%) | 12 (50%) |
| 4 | 120 | 98 | 100 | 20 | 112 | 8 |
| Type 1 | 3 (2.5%) | 2 (2%) | 2 (2%) | 1 (5%) | 2 (1.8%) | 1 (12.5%) |
| Type 2 | 32 (26.7%) | 25 (25.5%) | 26 (26%) | 6 (30%) | 29 (25.9%) | 3 (37.5%) |
| Type 3 | 85 (70.8%) | 71 (72.5%) | 72 (72%) | 13 (65%) | 81 (72.3) | 4 (50%) |
| 5 | 97 | 92 | 80 | 17 | 96 | 1 |
| Type 1 | 1 (1%) | 0 (0%) | 1 (1.25%) | 0 (0%) | 1 (1%) | 0 (0%) |
| Type 2 | 18 (18.6%) | 18 (19.6%) | 16 (20%) | 2 (11.8%) | 18 (18.8%) | 0 (0%) |
| Type 3 | 78 (80.4%) | 74 (80.4%) | 63 (78.7%) | 15 (88.2%) | 77 (80.2%) | 1 (100%) |
The reported p values are for all the categories in each column
*
Statistically significant
a
Quartile 1–3
b
only one lesion in this group