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. Author manuscript; available in PMC: 2023 Jun 14.

Published in final edited form as: Eur Urol. 2021 Jan 6;80(5):632–640. doi: 10.1016/j.eururo.2020.12.040

Table 3.

– Patterns of failure at the time of first recurrence

Pathogenic alteration	Patients, n (%)				p value
Pathogenic alteration	Pelvic n = 30	Abdominal node n = 18	Bone n = 55	Visceral n = 21

TP53	7 (23)	9 (50)	19 (35)	4 (19)	0.14
DNA double-strand break	4 (13)	5 (28)	12 (22)	10 (48)	0.04
WNT	1 (3)	0 (0)	7 (13)	7 (33)	0.004
PTEN/PI3K	8 (27)	6 (33)	17 (31)	7 (33)	0.9