FIGURE 5.

Activated and suppressed pathways identified by GSEA using the hallmark gene set in immune subtypes. A and B, Heat maps representing top scored pathways enriched in genes with expression increased and decreased in common in LUAD (A) and LUSQ (B). C and D, Top signatures of pathways with increased expression are shown in red; those for genes with decreased expression are shown in blue. Running enrichment scores for glycolysis, IFNα, IFNγ, K-ras signaling, and TGFβ signaling signatures as commonly activated pathways in immune subtypes of LUAD (C) and LUSQ (D).