Table 1.
Baseline characteristics
| Variables | Early flexible sigmoidoscopy ≤ 72 hours (n = 87) | Delayed flexible sigmoidoscopy > 72 hours (n = 25) | P-value |
|---|---|---|---|
| Patient characteristics | |||
| Age (years), mean (SD) | 39.1 (16.5) | 39.8 (18.4) | .84 |
| Female, n (%) | 39 (44.8) | 12 (48) | .78 |
| BMI, mean (SD) | 26.9 (6.7) | 25.3 (6.5) | .27 |
| Current smoker, n (%) | 3 (3.5) | 3 (12) | .08 |
| On IMM on admission, n (%) | 3 (3.5) | 3 (12) | .09 |
| Biologic-naïve, n (%) | 55 (63.2) | 16 (64) | .94 |
| Prior anti-TNF, n (%) | 26 (29.9) | 8 (32) | .84 |
| On chronic opioids, n (%) | 7 (8.1) | 1 (4) | .49 |
| On oral corticosteroids at time of admission, n (%) | 44 (50.6) | 12 (48) | .82 |
| Disease activity | |||
| Pancolitis, n (%) | 60 (68.9) | 20 (80) | .28 |
| Presence of extraintestinal manifestations (EIM), n (%) | 8 (9.2) | 1 (4) | .39 |
| Concomitant CMV infection, n (%) | 2 (2.3) | 1 (4) | .17 |
| Concomitant C. difficile infection, n (%) | 3 (3.5) | 1 (4) | .89 |
| C-reactive protein md/dL at presentation, mean (SD)a | 72.8 (71.5) | 98.8 (72.7) | .14 |
| Albumin g/dL at presentation, mean (SD)b | 3.4 (0.71) | 3.2 (0.67) | .13 |
| Mayo UC 3 endoscopic subscore, n (%) | 60 (68.9) | 18 (72) | .67 |
Abbreviations: anti-TNF, anti-tumor necrosis factor; BMI, body mass index; C. difficile, Clostridioides difficile; CMV, cytomegalovirus; IMM, immunomodulator; SD, standard deviation; UC, ulcerative colitis.
aData missing on 16 patients.
bData missing on 11 patients.