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Relationship between proprotein convertase subtilisin/kexin type 6 and clinically relevant idiopathic pulmonary fibrosis endpoints. (A and B) Higher peripheral blood gene expression (A) and circulating plasma protein concentration (B) are associated with reduced transplantation-free survival. CI = confidence interval; COMET = Correlating Outcomes with Biochemical Markers to Estimate Time-Progression in IPF.
