Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 30;14:1186016. doi: 10.3389/fphar.2023.1186016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Quesada-Simó, Garrido-Marín, Nos and Gil-Perotín.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of anti-CD20 therapies on GI mucosal microenvironment. The deleterious effect of anti-CD20 therapies could be explained by the depletion of the B-cell compartment because B cells in the GI mucosa may act as regulatory with a potential protective effect. B cells regulate cellular production of TNFα in colonic inflammation, produce anti-inflammatory cytokines such as IL-10, and have an adjuvant effect on regulatory T cell (Treg) function. Abbreviations: GI: gastrointestinal. Modified and made with Biorender.