Scheme 6.
Synthesis of naphthalene derivatives 39a–d a. a Reagents and conditions: (a) DMAP, 100 °C, 2 h, 16–38%; (b) LiOH, THF, H2O, rt, 12 h, 31–86%; (c) 3-(trifluoromethoxy)aniline, T3P, DIPEA, THF, rt, 12 h 17–27%.
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