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. 2023 Jun 13;9(6):e17264. doi: 10.1016/j.heliyon.2023.e17264

Table 1.

Performance of the 4-plex assay. Sensitivity and specificity of the luminex antibody assay for antigen in multiplex.

AUC 95% CI p value cut off Sensitivity % 95% CI Specificity % 95% CI
IgM S1 0.96 0.94–0.99 <0.0001 >201.90 83.87 72.79–91.00 95.00 83.50–99.11
S2 0.88 0.81–0.94 <0.0001 >1437 56.45 44.09–68.06 97.50 87.12–99.87
RBD 0.94 0.89–0.99 <0.0001 >2036 62.90 50.46–73.84 95.00 83.50–99.11
N 0.81 0.71–0.91 <0.0001 >1404 58.06 45.676–9.52 95.00 83.50–99.11
IgG S1 0.98 0.95–1.00 <0.0001 >335.70 96.77 88.98–99.43 97.50 87.12–99.87
S2 0.97 0.94–1.00 <0.0001 >4396 100.00 94.17–100.00 95.00 83.50–99.11
RBD 0.99 0.97–1.00 <0.0001 >1613 96.77 88.98–99.43 100.00 91.24–100.00
N 1.00 1.00–1.00 <0.0001 >1114 100.00 94.17–100.00 100.00 91.24–100.00