Table 1.
Performance of the 4-plex assay. Sensitivity and specificity of the luminex antibody assay for antigen in multiplex.
AUC | 95% CI | p value | cut off | Sensitivity % | 95% CI | Specificity % | 95% CI | ||
---|---|---|---|---|---|---|---|---|---|
IgM | S1 | 0.96 | 0.94–0.99 | <0.0001 | >201.90 | 83.87 | 72.79–91.00 | 95.00 | 83.50–99.11 |
S2 | 0.88 | 0.81–0.94 | <0.0001 | >1437 | 56.45 | 44.09–68.06 | 97.50 | 87.12–99.87 | |
RBD | 0.94 | 0.89–0.99 | <0.0001 | >2036 | 62.90 | 50.46–73.84 | 95.00 | 83.50–99.11 | |
N | 0.81 | 0.71–0.91 | <0.0001 | >1404 | 58.06 | 45.676–9.52 | 95.00 | 83.50–99.11 | |
IgG | S1 | 0.98 | 0.95–1.00 | <0.0001 | >335.70 | 96.77 | 88.98–99.43 | 97.50 | 87.12–99.87 |
S2 | 0.97 | 0.94–1.00 | <0.0001 | >4396 | 100.00 | 94.17–100.00 | 95.00 | 83.50–99.11 | |
RBD | 0.99 | 0.97–1.00 | <0.0001 | >1613 | 96.77 | 88.98–99.43 | 100.00 | 91.24–100.00 | |
N | 1.00 | 1.00–1.00 | <0.0001 | >1114 | 100.00 | 94.17–100.00 | 100.00 | 91.24–100.00 |