Fig. 5: The phenotype of HDV-specific and total CD8+ T cells correlates with inflammation.
Spearman correlation between (A) the frequency of terminally differentiated (CD57+) HDV-specific (left panel) and total CD8+ T cells (right panel) in the blood and HDV viremia, (B) the frequency of terminally differentiated (CD57+) HDV-specific (left panel) and total CD8+ T cells (right panel) in the liver and HAI score, (C) the frequency of NKG2D+ HDV-specific CD8+ T cells (left panel) and total CD8+ T cells (right panel) in the liver and HAI score, (D) the frequency of degranulating (CD107a+) CD8+ T cells in the liver and AST activity (left panel) and APRI score (right panel). AST: Aspartate aminotransferase; APRI: AST to platelet ratio index; HAI: histologic activity index; N.s: not significant.