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A. Comparison of mouse tumor weight at 28 days for WT (n = 20; white) and BKO (n = 20) KPC tumors. B. WT (n = 20; black) and BKO (n = 20; grey) mean (± standard error) tumor size (in mm3) over the 28-day growth period. C. Kaplan Meier survival curve for mice implanted with WT (n = 7; black) and BKO (n = 7; grey) KPC tumors. The dotted lines indicate the median survival. [ns = not significant, * = p < 0.05, ** = p < 0.01].
