Table 3. Univariate and multivariate linear regression analysis: Standardized Beta coefficients of independent variables assessed in the study group after receiving a 2nd dose of the ChAd vaccine (n = 63) and in the cohort participating in the post-booster follow-up (n = 40).
Parameters | Early follow-up– 14–21 days after receiving 2nd dose of ChAdOx1 vaccine, n = 63 | |||||
Univariate analysis |
Multivariate analysis* (adjusted R2 = 0.23) |
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B | SE | p | B | SE | p | |
age ≥ 60 | -0.01 | 0.10 | 0.953 | -0.02 | 0.11 | 0.869 |
seropositivity before the study started 1 | 0.21 | 0.06 | 0.001 | 0.17 | 0.06 | 0.008 |
smoking | -0.17 | 0.09 | 0.072 | 0.12 | 0.09 | 0.167 |
allergy | 0.06 | 0.13 | 0.654 | 0.00 | 0.12 | 0.967 |
obesity | 0.15 | 0.07 | 0.037 | 0.00 | 0.10 | 0.995 |
NFF | 0.11 | 0.05 | 0.026 | 0.11 | 0.05 | 0.057 |
FF | 0.13 | 0.05 | 0.020 | 0.14 | 0.06 | 0.036 |
Parameters | Post-booster follow-up—21 days after receiving the BNT162b2 booster, n = 40 | |||||
Univariate analysis |
Multivariate analysis** (adjusted R2 = 0.19) |
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B | SE | p | B | SE | p | |
age ≥ 60 | 0.09 | 0.08 | 0.258 | 0.10 | 0.09 | 0.272 |
seropositivity before the study started 1 | 0.13 | 0.05 | 0.027 | 0.06 | 0.06 | 0.333 |
smoking | -0.12 | 0.07 | 0.079 | 0.07 | 0.06 | 0.250 |
allergy | -0.01 | 0.11 | 0.962 | -0.02 | 0.10 | 0.854 |
obesity | 0.15 | 0.06 | 0.022 | 0.01 | 0.10 | 0.886 |
NFF | 0.09 | 0.04 | 0.022 | 0.09 | 0.05 | 0.094 |
FF | 0,08 | 0.05 | 0.086 | 0.06 | 0.06 | 0.319 |
1seropositivity before the study started–anti-SARS-CoV-2 IgG titers ≥ 10.00 AU/mL before the first vaccine dose
*Durbin-Watson parameter is equal 1.87
**Durbin-Watson parameter is equal 2.04.
Abbreviations. R–linear regression coefficient, B—logistic regression coefficient, SE–standard error, p–statistical significance, NFF—non-fat factor, FF—fat factor.