Table 4. – Predictors (at hospital admission) of invasive mechanical ventilation support by Poisson regression model with robust variance.
| Variables | Multivariate model 1 RR (95% CI) | Multivariate model 2 RR (95% CI) | Multivariate model 3 RR (95% CI) | Multivariate model 4 RR (95% CI) | Multivariate model 5 RR (95% CI) |
|---|---|---|---|---|---|
| Myocardial injury | 2.8607 (2.4221-3.3787)* | 2.6906 (2.1353- 3.3901)* | 2.5901 (2.1627-3.1021)* | 1.9018 (1.5842-2.2830)* | 1.8675 (1.5662-2.2268)* |
| Age | --- | 1.0057 (0.9983-1.0131)*** | 1.0034 (0.9976-1.0093)*** | 1.0068 (1.0002-1.0133)* | --- |
| Female sex | --- | 0.8889 (0.7492-1.0546)*** | 0.8697 (0.7492-1.0546)*** | 0.9398 (0.7852-1.1249)*** | --- |
| Overall comorbidities**** | --- | --- | 1.1781 (1.0936-1.2691)* | 1.1313 (1.0494-1.2196)** | 1.1295 (1.0488-1.2164)* |
| Respiratory rate | --- | --- | --- | 1.0369 (1.0254-1.0485)* | 1.0332 (1.0222-1.0443)* |
| Heart rate | --- | --- | --- | 1.0002 (0.9954-1.0051)*** | --- |
| Systolic blood pressure < 90 mmHg with no inotrope | --- | --- | --- | 0.4001 (0.1252-1.2781)*** | --- |
| Glasgow <15 | --- | --- | --- | 0.8320 (0.6109-1.1332)*** | --- |
| SF ratio | --- | --- | --- | 0.9980 (0.9960-0.9990)* | 0.9980 (0.9970-0.9990)* |
| C-reactive protein | --- | --- | --- | 1.0027 (1.0019-1.0034)* | 1.0030 (1.0020-1.0040)* |
| Hemoglobin | --- | --- | --- | 1.0111 (0.9641-1.0605)*** | --- |
| Neutrophils | --- | --- | --- | 1.0005 (1.0003-1.0006)* | 1.0004 (1.0002-1.0005)* |
| Platelet count | --- | --- | --- | 0.9980 (0.9970-0.9990)* | 0.9995 (0.9994-0.9997)* |
| Urea | --- | --- | --- | 0.9954 (0.9912-0.9997)** | --- |
| Lactate | --- | --- | --- | 0.9740 (0.9045-1.0487)*** | --- |
| Sodium | --- | --- | --- | 0.9869 (0.9688-1.0054)*** | --- |
| Bicarbonate | --- | --- | --- | 1.0439 (0.9752-1.1174)*** | --- |
| pH | --- | --- | --- | 0.0965 (0.0039-2.3727)*** | --- |
| pCO2 | --- | --- | --- | 0.9743 (0.9413-1.0084)*** | --- |
| D-dimer | --- | --- | --- | 0.9999 (0.9998-1.0000)*** | --- |
CI: confidence interval; RR: relative risk; SF ratio: peripheral oxygen saturation (SpO 2 )/fraction of inspired oxygen (FiO 2 ) ratio. *p<0.0001; **p<0.05; ***p>0.05; ****Hypertension, diabetes mellitus, obesity, coronary artery disease, heart failure, atrial fibrillation or flutter, cirrhosis, cancer, and previous stroke.