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. 2023 Jun 13;100(24):e2490–e2503. doi: 10.1212/WNL.0000000000207346

Figure 2. Age-Related Sex Differences in the Probabilities of Symptomatic Large Artery Steno-Occlusion vs Regional Infarct Probabilities.

Figure 2

(A) Probabilities of symptomatic steno-occlusion of the MCA, extracranial ICA, and vertebral artery with age: female vs male. (B) Infarct probabilities in the striatocapsular region (basal ganglia/internal capsule and corona radiata), cortex, and cerebellum with age: female vs male. Mixed-effects logistic regression analyses were performed with adjustment for prestroke modified Rankin Scale score, hypertension, diabetes, hyperlipidemia, atrial fibrillation, smoking, a history of prior stroke, percentage white matter hyperintensity volume, and onset to MR imaging time. Each dot and error bars (red for female patients and blue for male patients) indicate the adjusted mean probability and its 95% CIs, respectively. Green bars show the age distribution in this study cohort. *p < 0.05 for the adjusted difference between female patients and male patients. ICA = internal carotid artery; MCA = middle cerebral artery.