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. 2023 Jun 13;100(24):e2490–e2503. doi: 10.1212/WNL.0000000000207346

Figure 3. Association of Percentage Infarct Volume With the Incidence of Either END or Unfavorable Functional Outcome, With Stratification by Sex and Age.

Figure 3

(A) Analyses of END for all patients, younger patients (52 years or younger), and older patients (older than 52 years). (B) Analyses of unfavorable functional outcome (3-month modified Rankin Scale score >2) for all patients, younger patients (52 years or younger), and older patients (older than 52 years). Mixed-effects logistic regression analysis shows age-specific and percentage infarct volume–dependent sex differences in the incidence of either END or unfavorable functional outcome, with adjustment for age, prestroke modified Rankin Scale score, hypertension, diabetes, hyperlipidemia, atrial fibrillation, smoking, a history of prior stroke, percentage white matter hyperintensity volume, onset to MR imaging time, and revascularization therapy. Dots and error bars (red for female patients and blue for male patients) indicate adjusted mean incidences of either END or unfavorable functional outcome and their 95% CIs, respectively. Green bars show the distribution of percentage infarct volumes in this study cohort. *p < 0.05 for the adjusted difference between female patients and male patients. END = early neurologic deterioration.