Table 2.
Physicochemical characteristics of the liposomal formulations
| Formulation | Lipid composition | Lipid Molar Ratio | Z average (nm)a | Z potential (mV)b | PDIc | % EEd |
|---|---|---|---|---|---|---|
| Naïve Liposome | DMPC:DMPG:DOPE:Chol | 60:8:20:12 | 128 ± 0.6 | − 17 ± 0.1 | 0.28 | – |
| Lip-V1 | DMPC:DMPG:DOPE:Chol | 60:8:20:12 | 138 ± 0.8 | − 17 ± 0.1 | 0.26 | 74.1 ± 2.2 |
| Lip-V2 | DMPC:DMPG:DOPE:Chol | 60:8:20:12 | 141 ± 0.9 | − 29 ± 0.2 | 0.27 | 66.8 ± 4.7 |
| Lip-V3 | DMPC:DMPG:DOPE:Chol | 60:8:20:12 | 139 ± 0.5 | − 17 ± 0.4 | 0.27 | 74.8 ± 0.7 |
The results of triple measurements of each formulation are reported. The information is displayed as mean ± Standard deviation (S.D)
aThe size of liposomes (Z average)
bThe charge of liposomes
cPolydispersity index
dEncapsulation Efficiency (%)