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. 2023 Mar 8;4(5):317–328. doi: 10.1016/j.hroo.2023.03.001

Table 1.

Inclusion criteria

Inclusion category Inclusion definition
1. Drug-resistant symptomatic PAF
 a. Paroxysmal AF that terminates spontaneously or with intervention within 7 d of onset.
 b. Frequency  i. Physician documentation of recurrent PAF (2 or more episodes) within 6 mo, AND
 ii. At least 1 documented episode by a recording such as ECG, EM, Holter monitor or telemetry strip within 12 mo of enrollment.
 c. Drug-resistant Failed AAD treatment, meaning therapeutic failure of at least 1 AAD (class I to IV) for efficacy and/or intolerance
2. Age Patients who are ≥18 and ≤75 years of age on the day of enrollment.
3. Participation  i. Providing informed consent to undergo study procedures, AND
 ii. Participating in all examinations and follow-up visits and tests associated with this clinical study.

AAD = antiarrhythmic drug; AF = atrial fibrillation; ECG = electrocardiography; EM = event monitor; PAF = paroxysmal atrial fibrillation.