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. 2023 Jun 13;6:638. doi: 10.1038/s42003-023-05011-w

Fig. 1. scRNA-seq recovers canonical cell types from visceral adipose tissue (VAT) in humans and mice.

Fig. 1

a Aggregate UMAP of major cell types in the stromal vascular fraction (SVF) of human omental fat. b Aggregate UMAP of major cell types in the stromal vascular fraction SVF of mouse perigonadal fat. c Heatmap of the top 10 highest expressed genes in each cell type for human females (F) or males (M). d Heatmap of the top 10 highest expressed genes in each cell type for mouse females (F) or males (M). e UMAPs split by obesity status in humans. f Proportion of each cell type in lean or obese human samples. g UMAPs split by obesity status in mice. h Proportion of each cell type in lean or obese mouse samples. Values are mean ± SD in (f). n = 4 lean and 5 obese for (f) and n = 1 pooled sample from n = 10 mice fed normal chow diet (lean) and n = 1 pooled sample from n = 10 mice fed high-fat diet (obese) for (h).